## GENOUROB

We introduce an equipment for Automated Dynamic Laximetry (LDA). The simplest definition that we could attribute to **laximetry** is the following**: it is the objective evaluation of knee laxity**. The Dyneelax or GNRB are automated dynamic laximeters (arthrometer) designed to apply a reproducible force across the knee and mechanically measure the resulting displacement. These medical devices allow running dynamic tests on the knee. This characteristic makes this device unique because as it enables the user to **objectively evaluate** the **knee stability **and its **displacement differential.**

## DYNEELAX

The **DYNEELAX** robotic arthrometer is the first arthrometer that applies both **tibial translation** and **rotation **to run **dynamic** & **objective** **knee stability** assessments.

**DYNEELAX** is a **4 in 1** device as it allows **diagnosis**, **prevention**, **rehabilitation** and **follow-up** of patients suffering from knee ligament injuries. It is currently the most **accurate & reproducible** **knee ligament arthrometer** as it is the only one that is completely **automated** & **computerised**.

**Example of an ANTERIOR CRUCIATE LIGAMENT ASSESSMENT using the DYNEELAX**

Graph 1 shows the results obtained after performing tests on both knees of a patient with the **DYNEELAX**. The graph displays the **compliance curves** (=opposite of stiffness curves) obtained after applying several forces on the tibia of the patient (anterior tibial translation). The green curve represents the data collected on the healthy knee while the red curve represents the pathological knee. This is called **“dynamic analysis”** because calculation of the displacements of the tibia is done while applying different forces that put the **anterior cruciate ligament** under stress (from 0 to 200N for example) to enable the drawing of compliance curves (=opposite of stiffness curves). As a result, the bigger the side-to-side differential, the higher the chances of an anterior cruciate ligament tear. It is thus against this background that Genourob innovated while conceptualizing the **DYNEELAX**, the first **automated tibial translation** **arthrometer** for **dynamic assessment** of the anterior cruciate ligament

**Example of a KNEE ROTATION LAXITY ASSESSMENT using the DYNEELAX**

Graph 2 shows the curve results with its table chart obtained after performing tests on both knees of a same patient with the **DYNEELAX**. The graph shows the **curves** obtained after applying several **torques on the tibia** of the patient to perform a motorized tibial rotation. This is called a **dynamic analysis** because calculation of the degree of rotation of the tibia is done while applying different forces which put the **knee peripheral ligamentous structures** under stress. Therefore, the bigger the rotation degree differential, the higher the chances are that knee peripheral structures have been injured.

**How is DYNEELAX more accurate than any other arthrometer?**

Here is an example to answer this question :

The two graphs below show the results obtained on the knees of two different patients having suffered from knee ligament injuries after a DYNEELAX test. The green curves show the test results of the healthy knees whereas the red curves show the results of the pathological knees. As 134 N is the international reference force for assessing the ACL thanks to the KT1000, let us compare the displacement differential between both knees of both patients at this force. We can see here that the side-to-side displacement differential at 134 N is the same for both patients (1.5 mm). This should indicate that both patients are not suffering from a torn ACL. However, it not the case. The **DYNEELAX** indeed shows **innovation** & **precision **in this exact situation as it provide an **additional diagnosis method: the analysis of the slope of the curves**.

In fact, we can determine that Patient 1 has a stable knee while Patient 2 is unstable. Why?

Because on the graph of patient 1, the ACL compliance curves (=opposite of stiffness curves) are **parallel** and on the graph of patient 2 the ACL compliance curves (=opposite of stiffness curves) **diverge**. This indeed shows that patient 1 has two stable knees with a slight side-to-side difference in laxity that remains the same eventhough the force applied on the knee increases. **This indicates a stable knee**. However, patient 2 clearly shows an **increasing side-to-side difference in laxity** **correlated with the increase of the force applied on the knees, hence the objective diagnosis of an unstable knee**. This example purely states the efficiency of running dynamics tests against static tests on the knee. Considering the **slope differential between both compliance** (=opposite of stiffness) curves on behalf of the **displacement differential** between both knees ultimately leads to a much more accurate analysis of the state of the ACL in the knee.

**Usable PRE-OP & POST-OP…**

Consequently, the **DYNEELAX** places itself as the most advanced arthrometer for evaluating the state of the anterior cruciate ligament as it is the only device capable of assessing ACL laxity very soon after **surgery without any risk **thanks to its **controlled tibial translation **(maximum forces applied can be chosen: 89, 100, 134, 150, 200 Newtons). Doctors are indeed able to **follow the behaviour of the ACL graft during the first months following the surgery**, which is key to increasing the probability of gaining **knee stability**. Today’s surgical techniques indeed require a lot of time of recovering therefore making the **DYNEELAX **indispensable** **during **anterior cruciate ligament rehabilitation (ACL Rehab).**

**DYNEELAX main characteristics for optimal ACL assessment**

- Device using LDA® Method applying anterior tibial translation (Lachman’s Test) for ACL and
**knee stability objective**evaluation. **Dynamic**and**none-invasive**tests.- Automatic
**tibial displacement differential**and**compliance curves slope differential**calculation. - Registration of the
**patellar fixation force**and**patient foot / Base of the machine distance**for**reproducibility.** - Delivery with
**PC**and**LDA® Software.** - Thrust force from 1 to 200 N.
- Patient data automatically saved, results exportable as xls. files, pdf. format for great communication.
- Dimensions : 845 x 270 x 400mm / 15kg.

## GNRB

The anterior cruciate ligament (ACL) was for GENOUROB the first knee ligament intended to be studied using the **GNRB**. This arthrometer (aka. laximeter) has quickly become the reference in the **orthopaedic** field for studying the state of the ACL by applying an automated Lachman Test.

The anterior cruciate ligament (ACL) was for GENOUROB the first knee ligament intended to be studied using the GNRB. This arthrometer (aka. laximeter) has quickly become the reference in the orthopaedic field for studying the state of the ACL by applying an automated Lachman Test. Presently, the GNRB device provides the best precision in regards of knee ACL laxity assessement as it is the only arthrometer (aka. laximeter) able to objectively evaluate knee stability because of the dynamic tests it runs. While designing this tool, user friendliness was for us one of the major aspects that had to be taken into account. This consequently lead to many parameters and sensors being considered in order to guide the users while running dynamic tests. Thanks to these parameters and sensors, precise test reproducibility is now one of the top attributes the GNRB has to offer among many other. Further-more, the LDA® Method, which is an integral part of the GNRB, is perhaps what makes this device leader in the field of ACL analysis. The results given after a test are shown under the form of compliance curves (=opposite of the stiffness curves) accompanied by a table chart that generate sensible data to practitionner. This makes the tests easy-to-understand, to reproduce and it allows an evaluation with accurate figures of ACL laxity & knee stability.

**Example of an anterior cruciate ligament assessment using the GNRB**

Graph 1 shows the results obtained after performing tests on both knees of a patient with the **GNRB**. The graph displays the **compliance curves** (=opposite of stiffness curves) obtained after applying several forces on the tibia of the patient (anterior tibial translation). The green curve represents the data collected on the healthy knee while the red curve represents the pathological knee. This is called **“dynamic analysis”** because calculation of the displacements of the tibia is done while applying different forces that put the **anterior cruciate ligament** under stress (from 0 to 200N for example) to enable the drawing of compliance curves (=opposite of stiffness curves). As a result, the bigger the side-to-side differential, the higher the chances of an anterior cruciate ligament tear. In comparison, other arthrometers only collect data at a certain force (134 N for example). This is called **“static analysis”**. It is thus against this background that Genourob innovated while conceptualizing the **GNRB**, the first **automated tibial translation** **arthrometer** for **dynamic assessment** of the anterior cruciate ligament.

**Why is the GNRB arthrometer more accurate than any other arthrometer?**

Here is an example to answer this question : the two graphs below show the results obtained on the knees of two different patients having suffered from knee ligament injuries after a GNRB test. The green curves show the test results of the healthy knees whereas the red curves show the results of the pathological knees.

As 134 N is the international reference force for assessing the ACL thanks to the KT1000, let us compare the displacement differential between both knees of both patients at this force. We can see here that the side-to-side displacement differential at 134 N is the same for both patients (1.5 mm). This should indicate that both patients are not suffering from a torn ACL. However, it not the case. The GNRB indeed shows innovation & precision in this exact situation as it provide an additional diagnosis method: the analysis of the slope of the curves.

In fact, we can determine that Patient 1 has a stable knee while Patient 2 is unstable. Why?

Because on the graph of patient 1, the ACL compliance curves (=opposite of stiffness curves) are parallel and on the graph of patient 2 the ACL compliance curves (=opposite of stiffness curves) diverge. This indeed shows that patient 1 has two stable knees with a slight side-to-side difference in laxity that remains the same eventhough the force applied on the knee increases. This indicates a stable knee. However, patient 2 clearly shows an increasing side-to-side difference in laxity correlated with the increase of the force applied on the knees, hence the objective diagnosis of an unstable knee. This example purely states the efficiency of running dynamics tests against static tests on the knee. Considering the slope differential between both compliance (=opposite of stiffness) curves on behalf of the displacement differential between both knees ultimately leads to a much more accurate analysis of the state of the ACL in the knee.

The consequently places the GNRB as the most advanced arthrometer for evaluating the state of the anterior cruciate ligament. Besides, it is also the only device capable of assessing ACL laxity very after surgery without any risk thanks to its controlled tibial translation (maximum forces applied can be chosen: 89, 100, 134, 150, 200 Newtons). Doctors are thus able to follow the behaviour of the ACL graft over the months following the surgery, which is key to increasing the probability of gaining knee stability. Today’s surgical techniques indeed require a lot of time of recovering therefore making the GNRB indispensable during anterior cruciate ligament rehabilitation (ACL Rehab). If you are curious in knowing how a test is performed, click on the title below to see a video of a GNRB test.

**GNRB main characteristics for optimal ACL assessment**

- Device using LDA® Method applying anterior tibial translation (Lachman’s Test) for ACL and knee stability objective evaluation.
- Dynamic and none-invasive tests.
- Automatic tibial displacement differential and compliance curves slope differential calculation.
- Registration of the patellar fixation force and patient foot / Base of the machine distance for reproducibility.
- Delivery with PC and LDA® Software.
- Thrust force from 1 to 200 N.
- Patient data automatically saved, results exportable as xls. files, pdf. format for great communication.
- Dimensions : 845 x 270 x 400mm / 15kg.